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REVIEW ARTICLE
Year : 2018  |  Volume : 4  |  Issue : 3  |  Page : 164-170

Review of cardiac amyloidosis


Department of Cardiology, All India Institute of Medical Sciences, New Delhi, India

Correspondence Address:
Dr. Srikant Shivan
Department of Cardiology, All India Institute of Medical Sciences, New Delhi
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/jpcs.jpcs_68_18

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Cardiac amyloidosis is characterized by clinically significant extracellular amyloid infiltration of the heart that is commonly associated with multiorgan involvement depending on the type of amyloid. The deposits are derived from one of several amyloidogenic precursor proteins, and the prognosis of the disease is determined both by the organ(s) involved and the type of amyloid. Cardiac involvement represents the most important prognostic factor and thus an early diagnosis of amyloid heart disease is of utmost importance influencing further prognosis and management of the patients. The last decade has seen considerable progress in the understanding of amyloidosis. This review broadly aims to discuss clinical manifestations and diagnostics of amyloidosis with the main focus on treatment of amyloid cardiomyopathy.


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