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Year : 2018  |  Volume : 4  |  Issue : 2  |  Page : 73-76

Oligonucleotides: A new approach against undruggable cardiovascular disorders

Department of Cardiology, AIIMS, New Delhi, India

Correspondence Address:
Dr. Arvind Dambalkar
Department of Cardiology, AIIMS, New Delhi
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/jpcs.jpcs_40_18

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Oligonucleotides are short DNA or RNA molecules used for a variety of indications in medicine. They can be used for artificial gene synthesis, polymerase chain reactions, and DNA sequencing and can be used as molecular probes. They are usually found as small RNA molecules that function in the regulation of gene expression (e.g., microRNA). These antisense oligonucleotides, based on DNA or RNA chemistries, regulate gene expression by binding to an RNA target.

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